Dosing Calculator

Online Prescription Assistance

NxRx®

Online Prescription and Ordering System

NxDocuments

Training and Resource Library

Nx2me® Clinician Portal

Flowsheets and Reporting

Find a Home Training Program Support Contact Us

For Healthcare Professionals

Home Hemodialysis Customer Support: 866-697-8243

Peritoneal Dialysis Customer Support: 800-323-5188

Talk to a Patient Consultant About Home Dialysis: 888-200-6456

Home Hemodialysis Customer Support: 866-697-8243

Peritoneal Dialysis Customer Support: 800-323-5188

Talk to a Patient Consultant About Home Dialysis: 888-200-6456

  • Home Hemodialysis
    • What You Need to Know About Kidney Disease
    • How Dialysis Frequency and Duration Impact Your Heart Health
    • Solo/Independent Home Dialysis
    • Nocturnal Home Dialysis
  • Peritoneal Dialysis
    • About Peritoneal Dialysis
  • Home Dialysis Systems
    • NxStage VersiHD with GuideMe Software
    • NxStage VersiHD
    • System One Portable Hemodialysis Machine
    • How Does System One Work?
    • Nx2me Connected Health
  • Travel and Lifestyle
    • Traveling with Home Hemodialysis
    • Traveling with Peritoneal Dialysis
    • Watch and Read Patient Stories
    • The Patient Journey
  • Home Dialysis Resources
    • The Benefits of More Frequent Home Dialysis
    • Talk to a Patient Consultant
    • Frequently Asked Questions
    • Visits with Vanessa Podcast
    • Webinars
    • Atlas: Stories & Resources for Living Well
    • Kidney Disease Resources and Links
    • Service and Support
    • Find A Center
  • Care Partner Support
    • Becoming a Care Partner for a Loved One on Hemodialysis
    • Support for Care Partners of Patients on Home Hemodialysis
    • Help for Family and Friends of Patients on Dialysis
    • Turn to Respite Care When You Need It
    • Valuable Support Networks
Find a Home Training Program Support Contact Us

For Healthcare Professionals

Home Hemodialysis Customer Support: 866-697-8243

Peritoneal Dialysis Customer Support: 800-323-5188

Talk to a Patient Consultant About Home Dialysis: 888-200-6456

Home Hemodialysis Customer Support: 866-697-8243

Peritoneal Dialysis Customer Support: 800-323-5188

Talk to a Patient Consultant About Home Dialysis: 888-200-6456

Frequently Asked Questions

Frequently Asked Questions

Below are frequently asked questions about home dialysis therapies, NxStage® equipment, care partners, home dialysis training, and the risks and responsibilities associated with dialysis. Click on each section heading to review the FAQs pertaining to that topic.

  1. Therapy
  2. Equipment
  3. Care Partner
  4. Training

Home Dialysis Therapy FAQs

In this section, you’ll find answers to frequently asked questions about home dialysis, including what it is, its benefits, challenges, and available options. If you have additional questions, reach out to your doctor or contact a Patient Consultant at 888-200-6456.

Home dialysis is the option to receive dialysis treatments in the comfort of your home, rather than at a center.  

There are two types of home dialysis therapies to consider—peritoneal dialysis (PD) and home hemodialysis (HHD). Talk with your doctor and care team to determine if PD or HHD might be a good therapy option for your health and lifestyle needs. 

PD uses blood vessels in the lining of your abdomen to remove toxins and extra fluid from your blood. Typically, PD patients can perform therapy on their own at home. PD treatments are done daily, so waste and toxins in your blood don’t have a chance to build up as much between treatments, compared to in-center hemodialysis.

ICHD uses a machine to remove blood from your body, clean it, and return it to your body. Treatments are traditionally performed at a dialysis center 3 times a week, for about 4 hours per session.

HHD follows a similar treatment procedure as ICHD but is usually done in the comfort of your home, and more frequently, 5 or 6 days a week. More frequent hemodialysis may lead to improved health and quality-of-life outcomes.1 Your doctor may prescribe HHD to be performed during the day—with or without a care partner—or overnight while you and your care partner sleep, which is referred to as nocturnal HHD.

Studies have shown that there are several clinical and lifestyle benefits to more frequent home dialysis, including:

  • Greater schedule flexibility

  • Improved sleep quality2

  • Improved post-dialysis recovery time3

  • Improved appetite4

  • Increased likelihood to be on the kidney transplant list5

There are some risks with all medical procedures and treatments. Serious adverse events in home dialysis are relatively rare*. Home dialysis equipment is safe to use with both procedural steps and system alarms in place to help prevent any adverse events from occurring. In addition, your home training nurse will review all the precautions and procedures needed to avoid and prevent any adverse events. Patient retraining and periodic technique checks may also help mitigate these risks. Please review full risks and responsibilities below.

*Tennankore KK, et al. Am J Kidney Dis. 2015;65(1):116-121.

For most patients, supplies and equipment are covered by their insurance or Medicare, but it is important to review coverage with your insurance provider to learn more about what options are available to you. Your social worker and insurance coordinator can also help you with this process and identify opportunities for reducing costs. 

Many patients may be candidates for home therapy, including patients with pre-existing conditions or disabilities. Interested patients should discuss this with their care team, who can review their specifics needs and help determine what is best for them.  

If you choose to do home dialysis, you and/or your care partner(s) will be responsible for all aspects of the dialysis treatment from start to finish, including but not limited to:

  • Setting up the dialysis equipment

  • Cannulation (inserting needles)

  • Taking vitals

  • Responding to and resolving all system alarms with the help of Technical Support, if needed

  • Monitoring blood pressure

  • Maintaining a clean and safe environment for treatment

Both you and your care partner(s) will be trained by your provider so you’re equipped to respond to any health emergencies that might occur during treatment at home, including dizziness, nausea, hypotension (low blood pressure), and fluid or blood leaks. 

Your care and home training teams will work to train you as soon as possible. In some cases, training may begin in-center with an overview of each system and therapy, a review of the first few elements of training, and an opportunity to ask questions. You will go home after training is completed, and you and your care team feel you are ready.

There is no recognition or nomination program required to go home. If you are interested, start by talking to your physician to determine if home dialysis is right for you. Once you have a prescription from your physician, the center can introduce you to your home training team, who will help you get started. 

Some in-center clinics have a program called Experience the Difference. Ask your care team if this is something they offer. The program offers in-center hemodialysis patients the opportunity to have more frequent hemodialysis treatments in your own center for 1-2 weeks without giving up your current in-center time slot. During this time, you will discover and potentially experience some of the benefits made possible by dialyzing more frequently.

No. It may be an option for you to perform home dialysis without a care partner. PD, for example, is typically performed without the help of a care partner. Solo HHD during waking hours with a NxStage system is possible for many patients with additional training from their care team. Your care team will work with you to determine what is the best approach for you. 

Yes. Home dialysis offers much greater schedule and lifestyle flexibility, as you are not tied to a specific time slot on your treatment days. You can work with your doctor to determine the treatment schedule that works best for you.

Every prescription is based on the individual’s particular health and lifestyle needs. Work with your doctor to determine what home modality option best fits your clinical and lifestyle needs and how often you will be required to treat. 

When starting dialysis, there are different types of dialysis access to consider. PD uses one type of access – a PD catheter. This is a flexible tube placed in your abdomen, with a small piece of tubing left outside of the body. People on HD typically use an arteriovenous (AV) fistula or graft. There is some flexibility for patients with special health requirements. Talk to your doctor about which access type is best for you.

You and your doctor will discuss your specific health and lifestyle needs, and what is important to you. Based on those needs, your doctor will determine the specifics of your prescription. It is important to have regular conversations with your doctor about your treatments and any negative symptoms you experience as your prescription should be updated based on how you are feeling.

Past abdominal surgery doesn’t automatically disqualify a patient from doing PD. Interested patients who have had a prior surgery can work with their doctor to assess their ability to do PD treatments. 

Patients start home dialysis with a wide range of residual kidney function. Talk to your doctor to see what treatment option is right for you. 

It is important that the treatment area remain clean to help avoid the risk of an infection. Most often, people choose to designate one room or area as their treatment space and keep it clean. This does not mean the entire house or dwelling needs to be spotless at all times. If you choose to perform home dialysis, your home training care team will provide education around how to properly care for your designated treatment area. 

Many patients on home therapies participate in water activities. Follow the guidance of your doctor regarding what water activities can be enjoyed safely.

Yes, whether you have chosen PD or HHD, you are allowed to take showers. You need to wait for a new catheter site to heal before showering. Always follow the guidance of your doctor regarding what method is best based on your specific care plan and needs.

There are no home decor restrictions to home therapy, including carpet.

There is no education requirement to be on a home modality, and both HHD and PD patients have a wide range of education backgrounds. Your care team will provide training and support so that you are well prepared to perform home dialysis. 

Typically, no physical home modifications, such as plumbing or electrical, are needed for HHD with a NxStage system or for PD. 

Many people who select a home therapy report feeling better physically when performing more frequent treatments1, and studies have shown that there is a higher likelihood of receiving a transplant for both PD and HHD.6,7 

NxStage Equipment FAQs

NxStage Versi®HD with GuideMe Software, NxStage VersiHD, and NxStage System One™ are home hemodialysis machines designed with patients in mind, to be simple, flexible, and portable. If you don’t find the answers to your questions or need additional support, contact our customer support team at 866-697-8243. 

When you talk with your doctor and care team about starting home dialysis, you will be entered into a home training program and given a prescription and dialysis machine that you keep in your home.

NxStage VersiHD with GuideMe Software, NxStage VersiHD, and NxStage System One are home hemodialysis machines designed with patients in mind, to be simple, flexible, and portable.

The NxStage System One functions similar to traditional in-center hemodialysis machines. It removes blood from the body, filters it, and returns the cleaned blood back to your body. The System One cycler and the VersiHD cycler contain the system controls that help you make adjustments before and during treatment. The steps in the treatment process will also be tailored specifically to you and your needs by your doctor and care team. 

Yes! Travel is one of the many possibilities you can explore when you use the NxStage systems. With a little extra planning to make sure you can continue dialysis treatment while you’re away, you may be able to travel via an airplane, ship, or car. Talk with your care team for assistance if you are interested in planning a trip. 

Nx2me Connected Health is an application that helps you stay connected to your clinician and care team by securely collecting and sharing health information in a timely manner. The application uses Wi-Fi, and if you don’t have access to Wi-Fi, a cell data plan is available. 

Patients have access to Fresenius Medical Care (FMC) Technical Support and Customer Service for peritoneal dialysis (PD) equipment questions and NxStage Technical Support and Customer Service for HHD equipment questions. See below for contact information for FMC. 

FMC Product Training and Technical Support 
800-227-2572

FMC Customer Service 
800-323-5188

FMC Patient Consultants
888-200-6456

FMC Technical Support 
866-697-8243 
Opt. 1: Technical Support 
Opt. 2: Customer Service 

The NxStage dialysis systems are designed to fit easily in your home. 

  • The NxStage VersiHD measures approximately 18 inches high by 15 inches wide by 16 inches deep and weighs less than 80 pounds8. It can easily fit into most rooms without any home modifications and can also be packed into a car or checked for airplane travel (with the appropriate preliminary steps and protective case). 

  • The PureFlow SL dialysate purification system is about the size of an end table, and the NxStage cycler sits on top of it. The PureFlow SL is not portable for travel.

In addition to the machines, you will also need storage space for the disposable supplies, such as cartridges, sacks of concentrated dialysate, and bags of premixed dialysate (for backup and travel), as well as access-related supplies and saline bags.

There are no restrictions on the use of well water for home dialysis patients using NxStage equipment. Patient source water is tested while the patient is training, and any necessary adjustments can often be made, depending on the quality of the water to ensure it meets the U.S. EPA Safe Drinking Water Act (SDWA) guidelines. There may be cases where certain source water does not meet the outlined standards and, in those cases, bagged dialysate may be used for treatments.

VersiHD is the latest version of the home hemodialysis cycler from NxStage. Designed for simplicity, the VersiHD cycler’s compact size and functionality are complemented by a touchscreen interface that allows for responsive key presses and advanced on-screen displays. While the touchscreen buttons are the same buttons patients are familiar with across all of our cycler systems, on the VersiHD touchscreen, the buttons illuminate only when they can be adjusted or pressed during operation, enhancing clarity and confidence during treatment. The VersiHD and System One S cyclers are also capable of higher dialysate flow rates compared to previous systems.

Some storage space is needed for treatment supplies. Many patients use a closet or under-bed area for storage, and clinic staff may be able to help access space if needed. Home patients treat in many types of settings, from large homes to small apartments, RVs, and mobile homes. If you have any concerns or questions, reach out to a NxStage Patient Consultant.

Many patients are also pet owners. However, it is recommended to keep pets out of the dialysis treatment area.

Care Partner FAQs 

In this section, you’ll find answers to frequently asked questions about care partners, including what a care partner is and how to become one. If you don’t find the answers you’re looking for, contact one of our patient consultants at 888-200-6456 or contact our customer support team at 866-697-8243.

Some patients may require a care partner to help them perform home dialysis. He or she doesn’t need to be a medical professional and also doesn’t have to be a live-in relative, spouse, or family member. Your care partner can be a family member, friend, neighbor, work colleague, church friend, or even a business associate. 

No, not all patients need a care partner. If you and your physician sign off on solo home dialysis during waking hours, a care partner is not required. However, many people on home therapy prefer to perform their own treatments but choose to have a care partner present in the event of a problem or issue during treatment.

If you are interested in learning more about being a care partner, fill out this form or call 1-888-200-6456 to talk to an expert. You will also receive formal training if you decide to become a care partner so that you are prepared to assist your loved one with treatment. 

While you’re caring for someone else, you also need to take care of yourself. NxStage Atlas is a health and wellness website that focuses on mind, body, and spirit and is a great resource for patients and care partners alike. You can also speak to one of our Patient Consultants for support. Our consultants are current or former NxStage patients or care partners. 

There are no medical training requirements for care partners. Care partners can be spouses, friends, or neighbors. The only requirement is that they attend training sessions for the specific duties they decide to take on. 

Home Dialysis Training FAQs

In this section, you’ll find answers to frequently asked questions about home dialysis training. If you have additional questions, contact your doctor or care team or call our customer support team at 1-866-697-8243.

Even if a center doesn’t offer home training, center staff can often connect an interested patient to a home training program in their network. It is possible for patients to move to a home training center—they are not required to stay at their center, especially if another therapy option might be a better fit for them.

This is a common concern, however, many people with a needle phobia have successfully trained on home dialysis, overcome their fears, and succeeded at home. Cannulation teams and experts in certain centers can also help address these concerns.

For some people, the decision to go home is made with their doctor prior to needing dialysis, while others make the decision later in their dialysis journey. There is no defined progression or pathway for treatment plans. Talk to your care team if you are interested in learning more about home dialysis. 

Patients are trained by their dialysis center. The pace of training will be adjusted to each individual learner, but typically takes about 4 weeks for home hemodialysis (HHD) and 2 weeks for peritoneal dialysis. During training you will learn about the various products, how to handle emergencies, disease education, and more. Please note that you will not go home until both you and your care team are confident you can perform your treatment safely.

Training times vary and depend on patient experience. In a study of HHD patients, half of the patients were trained on the NxStage system itself in 10 days or less. This is a testament to NxStage systems being designed for simplicity and ease of use by patients at home. There are other components to learning about home dialysis that can increase training time to 2-4 weeks. Healthcare training teams will always ensure that patients are comfortable and can safely perform all aspects of their treatments before going home.9

Your center, care team, technical support, and customer service are all available resources that you can access while dialyzing at home.

If you are experiencing a medical emergency during a treatment, you should contact 911. For equipment concerns, or issues, you can contact Technical Support 24/7, 365 days a year. Customer service is available Monday to Friday during normal business hours to answer questions regarding deliveries, inventory, or travel.

Risks and Responsibilities

The reported benefits of peritoneal dialysis may not be experienced by all patients.

Peritoneal dialysis does involve some risks that may be related to the patient, center, or equipment. These include, but are not limited to, infectious complications. Examples of infectious complications include peritonitis and exit-site and tunnel infections. Non-infectious complications include catheter complication such as migration and obstruction, peritoneal leaks, constipation, hemoperitoneum, hydrothorax, increased intraperitoneal volume, and respiratory and gastric issues. It is important for healthcare providers to monitor patient prescriptions and achievement of adequate fluid management goals. Patients should consult their doctor to understand the risks and responsibilities of performing peritoneal dialysis.


Patients should review the following information carefully and discuss it with their doctors to decide whether home hemodialysis with NxStage® systems is right for them.


Users should weigh the risks and benefits of performing home hemodialysis with NxStage systems.

  • Medical staff will not be present to respond to health emergencies that might happen during home treatments, including, among other things, dizziness, nausea, low blood pressure, and fluid or blood leaks.
  • Users may not experience the reported benefits of home, more frequent, or nocturnal hemodialysis with the NxStage systems.
  • The NxStage systems require a prescription for use.

 

 
Users will be responsible for all aspects of their hemodialysis treatment from start to finish.
 
  • Medical staff will not be present to perform home treatments. Users will be responsible for, among other things, equipment setup, needle insertions, responding to and resolving system alarms, system tear-down after treatment, monitoring blood pressure, ensuring proper aseptic technique is followed, and following all the training material and instructions that nurses provide.

 

Users will need additional resources to perform home hemodialysis.

  • Users will need a trained care partner to be present during your treatment at home (unless their doctor prescribes “solo/independent” home hemodialysis, described below).
  • Users must have a clean and safe environment for their home treatments.
  • Users will need space in their home for boxes of supplies necessary to perform home hemodialysis with NxStage systems.

 

Certain forms of home hemodialysis have additional risks.

  • If a doctor prescribes home hemodialysis more than 3 times a week, vascular access is exposed to more frequent use which may lead to access related complications, including infection of the site. Doctors should evaluate the medical necessity of more frequent treatments and discuss the risks and benefits of more frequent therapy with users.
  • If a doctor prescribes “solo/independent” home hemodialysis without a care partner during waking hours, risks of significant injury or death increase because no one is present to help users respond to health emergencies. If users experience needles coming out, blood loss, or very low blood pressure during solo/independent home hemodialysis, they may lose consciousness or become physically unable to correct the health emergency. Users will need additional ancillary devices and training to perform solo/independent home hemodialysis.
  • If a doctor prescribes “nocturnal” home hemodialysis at night while the user and a care partner are sleeping, risks increase due to the length of treatment time and because therapy is performed while the user and a care partner are sleeping. These risks include, among other things, blood access disconnects and blood loss during sleep, blood clotting due to slower blood flow or increased treatment time or both, and delayed response to alarms when waking from sleep. A doctor may need to adjust users’ medications for nocturnal home hemodialysis, including, among other things, iron, Erythropoiesis-Stimulating Agents (ESA), insulin/oral hypoglycemics, anticoagulants, and phosphate binders.

REFERENCES

  1. Daugirdas, John T.; Blake, Peter G.; and Ing, Todd S., “Handbook of Dialysis (5th ed.)” (2015).
  2. Jaber, B.L., Schiller, B., Burkart, J.M. et al, Impact of short daily hemodialysis on restless legs symptoms and sleep disturbances. Clin J Am Soc Nephrol. 2011;(6):1049–1056.
  3. Jaber BL, Lee Y, Collins AJ, et al. Effect of daily hemodialysis on depressive symptoms and post-dialysis recovery time: interim report from the FREEDOM (Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements) Study. Am J Kidney Dis. 2010;56(3):531-539.
  4. Spanner E, Suri R, Heidenheim AP, Lindsay RM. The impact of quotidian hemodialysis on nutrition. Am J Kidney Dis. 2003;42(1 suppl):30-35.
  5. Choi SJ, Obi Y, Ko GJ, et al. Comparing Patient Survival of Home Hemodialysis and Peritoneal Dialysis Patients. Am J Nephrol. 2020;51(3):192-200. doi:10.1159/000504691.
  6. Rydell, H., Ivarsson, K., Almquist, M., Clyne, N., & Segelmark, M. (2019). Fewer hospitalizations and prolonged technique survival with home hemodialysis- a matched cohort study from the Swedish Renal Registry. BMC Nephrology, 20(1), 1–8.
  7. Mehrotra R, Chiu YW, Kalantar-Zadeh K, Bargman J, Vonesh E. Similar outcomes with hemodialysis and peritoneal dialysis in patients with end-stage renal disease. Arch Intern Med. 2011;171(2):110-118.
  8. NxStage data on file, July 2021.
  9. Cherukuri, S., Bajo, M., Colussi, G., Corciulo, R., Fessi, H., Ficheux, M., Slon, M., Weinhandl, E., & Borman, N. (2018). Home hemodialysis treatment and outcomes: Retrospective analysis of the Knowledge to Improve Home Dialysis Network in Europe (KIHDNEy) cohort. BMC Nephrol. 2018;19(1):262. https://doi.org/10.1186/s12882-018-1059-2

APM2100 Rev. G

Quick links

Careers

Risk and Responsibilities 

CA Supply Chain Act and UK Modern Slavery Act

Do Not Sell My Personal Information

Limit the Use of my Sensitive Personal Information

Consumer Health Data Privacy Statement 

Opt-Out of Sale

Opt-Out of Targeted Advertising

Opt-Out of Profiling

Our Offices

350 Merrimack Street
Lawrence, MA 01843
United States 

350 Merrimack Street
Lawrence, MA 01843
United States 

920 Winter Street
Waltham, MA 02451
United States

920 Winter Street
Waltham, MA 02451
United States

1-866-NxStage (697-8243)

1-866-NxStage (697-8243)

Contact

All Contact Information

All Contact Information

Social Media

Social Media

Facebook

X

Youtube

LinkedIn

© 2025 Fresenius Medical Care. All Rights Reserved.

© 2025 Fresenius Medical Care. All Rights Reserved.

Privacy Statement

Terms of Use

Cookie Settings